Skin immunoglobulin deposition following intravenous immunoglobulin therapy in toxic epidermal necrolysis
نویسندگان
چکیده
منابع مشابه
Levofloxacin-induced toxic epidermal necrolysis treated with intravenous immunoglobulin.
Dear Editor, Toxic Epidermal Necrolysis (TEN) is a rare, fulminating rash with a mortality rate of 35%.1 It is predominantly medication-induced; allopurinol, ampicillins, anticonvulsants and non-steroidal anti-inflammatory drugs are commonly implicated. Fluoroquinolones are widely used, have a broad coverage and have a low incidence of serious adverse effects. Levofloxacin, a L-racemic isomer o...
متن کاملCephalosporin-Induced Toxic Epidermal Necrolysis Treated with Intravenous Immunoglobulin
Toxic epidermal necrolysis (TEN) is a life-threatening cutaneous reaction to various medications, including antipsychotics and antibiotics. While cephalosporin-induced TEN is very rare, we present a case of cefepime-induced TEN. There are several commonly used therapies for TEN, including immunosuppressive agents and intravenous immunoglobulin (IVIG), but their true efficacy has not been proven...
متن کاملTreatment of toxic epidermal necrolysis with intravenous immunoglobulin.
Toxic epidermal necrolysis is a severe adverse drug reaction that produces extensive mucocutaneous damage, with full-thickness epidermal detachment, and has many clinical similarities to severe burn injuries. The treatment is mainly supportive and aimed at preventing complications while the disease takes its natural course, and the skin reepithelializes. Much interest exists in the development ...
متن کاملintravenous immunoglobulin in the treatment of lamotrigine- induced toxic epidermal necrolysis
toxic epidermal necrolysis is a potentially life-threatening disease, which needs necessary treatment. we present a 12 years old female who was a known case of idiopathic generalized tonic-clonic convulsion and presented with fever, diarrhea and generalized erythematous eruption after 2 weeks of being under treatment with maintenance doses of lamotrigine (ltg) and valproate (vpa). the eruption ...
متن کاملIn a patient with toxic epidermal necrolysis, does intravenous immunoglobulin improve survival compared with supportive care?
Clinical Question: A 67-year-old Chinese man presented with pain and widespread skin erythema and detachment. A clinical diagnosis of toxic epidermal necrolysis (TEN) was made, which was supported by skin biopsy findings. The TEN was thought to be due to recent initiation of lamotrigine for mild epilepsy, and the drug was stopped immediately. The severity of TEN, measured by the Severityof-Illn...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2006
ISSN: 0906-6705,1600-0625
DOI: 10.1111/j.0906-6705.2006.00426.x